Case Control Study Script
1. Zoom: Scientist with time machine and no cause/effect sign
Hot Spot: Observation study = observatory; retrospective study = retro outfit and turning back time; case control doesn’t demonstrate cause/effect = no cause/effect sign
Information Script: An observational study, a case control study is one in which two groups are compared on the basis of a speculative causal quality. Usually retrospective in nature, the study does not actually prove cause and effect. The observatory will help you to remember that we're looking at observation studies, and Wanda's retro outfit will provide a visual cue for retrospective studies. Case control doesn't demonstrate cause and effect, and the no cause/effect sign will aid in recalling that.
Story Script: Dr. Wanda Wayback loved the 1960s so much she can’t wait to return. She’s throwing a cause/effect understanding of time out the window and seeing it instead as a retrospective cycle. Using her Wayback Machine at the observatory, Dr. Wayback has donned her favorite retro bellbottoms and go-go boots for a wild ride back to see how medicine worked in the Age of Aquarius!
2. Zoom: Man with zebra briefcase and hand, and two other men with briefcases
Hot Spot: case = suitcase; diseased = zebra arm
Information Script: Instead, it compares two populations—one with a specific medical condition to one without. The subjects with the medical condition are referred to as the “cases,” while those without the condition are the “controls.” A case is shown here by the suitcase, and the zebra arm will help you to remember that it is diseased.
Story Script: And she’s arrived just in time! Turns out the Mad Men suit and tie crowd is in need of a little modern medicine—a top exec is experiencing a mysterious di-zebra! Zebra Fever, a skin condition, has Mr. Case in a panic, and Bill and Ted, wealthy brothers and CEOs of Control Group Ltd., are reconsidering that merger….
3. Zoom: Dr. Wayback interviewing the three men
Hot Spot: diseased & non-diseased = zebra and non-zebra rash
Information Script: Both are surveyed and interviewed on facts that might draw associations to a factor for that disease. In this case, the doctor is looking for feedback from both the zebra and non-zebra rash, or the diseased and non-diseased participants.
Story Script: Dr. Wayback decides to interview both Mr. Case and the Control Group brothers to try and determine what’s causing the Zebra Fever—stats, facts, where they’ve traveled over the past six months, anything that could get her to the bottom of this case. There are no easy answers, and she’s running out of funding.
4. Zoom: Dr. Wayback controlling the brothers and Mr. Case at the craps table
Hot Spot: control group = controller; odds ratio = gambling table; higher odds = zebra arm throwing dice
Information Script: Results of a case control study can help identify an odds ratio, shown here by the zebra arm throwing the dice, for a particular medical condition. This measurement quantifies the incidence of relative risk that an outcome will occur, given a causative factor. The controller in this picture represents the control group, while the odds ratio is seen in the gambling table.
Story Script: One interesting symptom of Mr. Case’s mysterious malady? The odds are always in his favor—a weekend in Atlantic City proves the man just can’t lose at the craps table when he throws with that diseased zebra arm of his! Suddenly, Dr. Wayback sees a path that will change the future of medicine—with remote control of the brothers, she’s got their minds and wallets both opened. Between Mr. Case’s luck and the brothers’ fortune, funding for her cause is ensured for at least another half century! Groovy!